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KMID : 0388420040140010161
Konkuk Journal of Medical Sciences
2004 Volume.14 No. 1 p.161 ~ p.168
Evaluation of diabetic complication throug hanalysis of heart rate variability
Kim Jong-Moon

Lee In-Sik
Kim Jong-Hoon
Lee Jeong-Mo
Chung Jin-Sang
Abstract
Objectives: The purpose of the present study was to investigate relationship between autonomic neuropathy and diabetic complication through analysis of HRV(heart rate variability) of diabetic patients, and ultimately to investigate effectiveness of HRV analysis on evaluation and prediction of diabetic peripheral neuropathy.

Methods: We performed electromyogram, blood analysis and HRV test with 30 diabetic patients. By comparing SDNN(standard deviation of RR interval) of HRV, we analyzed the relationship between this parameter and duration of diabetes, age, and results from electromyogram.

Results: 1) Averages of patients¡¯ age and the duration of diabetes were 56.12 ¡¾ 10.37, 14.58 ¡¾ 10.16, respectively. The relationship between each parameter of HRV was not significant(r<0.4). 2).When patients were classified according to the presence or the absence of H-reflex abnormality, peripheral neuropathy, gastrointestinal symptom When patients were classified by the degree of H-reflex abnormality and BUN(blood urea nitrogen), SDNN had reverse relationship to each other.

Conclusion: Our results demonstrate HRV test shows statistically significant differences according to the absence or presence of diabetic peripheral neuropathy, gastrointestinal symptom. Therefore, we expect HRV analysis might be used as an efficient method to detect diabetic peripheral neuropathy, gastrointestinal disease, since it is relatively easy and convenient for both doctor and patient.
KEYWORD
heart rate viriability, diabetes, neuropathy
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